Nephrology

NCT05082584 – Study to Evaluate the Safety and Efficacy of Oral Vadadustat in Pediatric Participants With Anemia of Chronic Kidney Disease Naive to Erythropoiesis-Stimulating Agents (CORRECTION)

NCT05732727 – Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease

Patient cohort

DNA samples from patients with SRNS

iPS cells

R140Q podocin (KI mouse model) – Nphs2Flox/Flox (inducible KO mouse model)

> 2500 patient cohort

DNA from patients with Alport Syndrome

Fribroblasts samples from patients with Alport Syndrome

> 100 families with Alport syndrome

DNA samples from patients with

Mouse model (please contact us)

Ctns KO mouse model

DNA samples from patients with Cystinosis

iPS cells – Urinary renal epithelial cells (UREC) – Knock-in HEK293 cells with mutations from patients (CRISPR)

>150 family cohort

NCT04125927 – Cystadrops in Pediatric Cystinosis Patients From Six Months to Less Than Two Years Old (SCOB2)

NCT05545774 – Neuromuscular Characterisation in Late Adolescent and Adult Cystinosis Patients

Methods for treating diseases associated with ciliopathies

> 1500 patients with NPH

DNA samples from patients with Renal Cystic Dysplasia

Patient cohort (CAKUT

DNA samples from patients

CAKUT (Congenital Anomalies of the Kidney and the Urinary Tract)

NCT03970577 – RItuximab From the FIRst Episode of Idiopathic Nephrotic Syndrome (RIFIREINS)

NCT05786768 – Efficacy and Safety of Obinutuzumab Versus Rituximab in Childhood Steroid Dependant and Frequent Relapsing Nephrotic Syndrome (OBIRINS)

Patient cohort

Patient cohort

NCT05312879 – Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1- Mediated Proteinuric Kidney Disease Mediated Proteinuric Kidney Disease

Patient cohort

NCT04147871 – Study Evaluating Patients With Cystinuria and Efficacy and Safety Exploratory Study in the Youngest Children

NCT05747274 – SRDK0921_ Analytical Performance Study

NCT04851145 – Mass Spectrometry-based Proteomics in Microvascular Inflammation Diagnosis in Kidney Transplantation.

NCT04851145 – Mass Spectrometry-based Proteomics in Microvascular Inflammation Diagnosis in Kidney Transplantation.

NCT04181710 – Evaluation of a Marine OXYgen Carrier for Organ Preservation

NCT04877288 – A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen and Their Adherence to Immunosuppressive Medications

NCT04581278 – Validation Study of the Feasibility of an Integrated Diagnostic System of Anatomo-pathological Lesions – Including Rejections – Appearing in Renal Grafts in the First Year of Transplant for Applicability in Routine Clinical Practice : KTD Innov-2 Study

NCT05977387 – Pediatric Kidney Transplant

NCT04774575 – Quantify the Benefits of Biomarkers in Routine Patient Care in Kidney Transplant Recipients

NCT05369975 – Efficacy and Safety in Imlifidase Desensitized Kidney Tx Patients Including Two Non-Comparative Reference Cohorts

NCT05635136 – Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography a Comparison to Conventional Histopathological Findings in Kidney Transplant Recipients (HARBOR)

NCT05073913 – Vascular Remodeling After Living Kidney Donation Study

NCT05513807 – Graft Acute Kidney Injury: Vitamin B3 to Facilitate Renal Recovery In the Early Life of a Transplant (GABRIEL)

NCT05753930 – Evaluation of respiratory function in children with renal transplantation: a prospective multicenter French study

NCT05112770 – AI for Allograft Diseases Diagnosis and Prognosis After Kidney Transplantation

NCT05672550 – Dose-adjustment of Enoxaparin by a Bayesian Pharmacological Approach in Pediatric Kidney Transplant Recipients (OPTI-TREX)