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Imagine's Offers

The database may not be exhaustive, please do not hesitate to contact us !

  • Anticoagulants
    Genotype Phenotype

    • Observational trials

       

      ENNOBLE-ATE (DU176b-C-U313) Edoxaban VS SOC, 7 patients

      Sponsor DAIICHI SANKYO

       

      CANNINES (B00661037) Apixaban

      Sponsor Pfizer

    Targets
    Therapeutics
    Clinical trials

  • Pulmonary hypertension in children
    Genotype Phenotype

    • Cohorts

      Please, contact us

    • Observational trials

       

      TOPP Registry: >90 pediatric patients enrolled

      Sponsor Actelion

       

      ZOHO Database : 427 patients

      Sponsor M3C

       

      ITINERAIR Registry : 52 patients enrolled

      Sponsor Société Française de Cardiologie

       

      CARREG (CARdiac congenital defects and REGulation genes) Registry: 4,398 patients

      Sponsor ARCFA

    • Patient samples

      Please, contact us

    Targets
    Therapeutics
    Clinical trials

    • NCT

       

      RUBATO (AC-055H301) Macitentan vs placebo Phase III

      Sponsor ACTELION

       

      RUBATO OL (AC-055H302) 

      Sponsor ACTELION

       

      SALTO (AC-A065A310) Selexipag vs Placebo Phase III

      Sponsor JANSSEN-CILAG

       

      SELEXIPAG PEDIATRIC (AC-065A203) Selexipag

      Sponsor ACTELION

       

      TOMORROW Study Macitentan Phase III

      Sponsor Actelion

  • Congenitally corrected transposition of great arteries (CCTGA)
    Genotype Phenotype

    • Cohorts

      Please contact us

    Targets
    Therapeutics
    Clinical trials
    Atrio Ventricular Canal Defect (AVCD)
    Genotype Phenotype

    • Cohorts

      Please contact us

    Targets

    • In vivo models

      Nodal inactivation (conditional KO mouse model)

    Therapeutics
    Clinical trials
    Double Outlet Right Ventricle (DORV)
    Genotype Phenotype

    • Cohorts

      Please contact us

    Targets

    • In vivo models

      Nodal inactivation (conditional KO mouse model)

    Therapeutics
    Clinical trials
    Transposition of the great arteries (TGA)
    Genotype Phenotype

    • Cohorts

      Please contact us

    Targets

    • In vivo models

      Nodal inactivation (conditional KO mouse model)

    Therapeutics
    Clinical trials
    Criss-cross heart
    Genotype Phenotype

    • Cohorts

      Please contact us

    Targets
    Therapeutics
    Clinical trials

  • Heterotaxia
    Genotype Phenotype

    • Cohorts

      Please contact us

    Targets

    • In vivo models

      Ift20 inactivation (KO & conditional KO mouse models)

      Nodal inactivation (conditional KO mouse model)

    Therapeutics
    Clinical trials
    Situs inversus
    Genotype Phenotype

    • Cohorts

      Please contact us

    Targets
    Therapeutics
    Clinical trials

  • Heart failure in children
    Genotype Phenotype

    • Cohorts

      Please, contact us

    • Patient samples

      Please, contact us

    Targets

    • In vivo models

      Fat4 inactivation (conditional KO)

    • Specific targets

      Fat4, Amotl1

    Therapeutics
    Clinical trials

    • NCT

       

      PANORAMA (CLCZ696B2319) - LCZ (Entresto) VS Enalapril - Phase III pediatric patients

      Sponsor Novartis

       

      PANORAMA EXT (CLCZ696B2319E1)

      Sponsor Novartis

  • Other cardiac congenital defects
    Genotype Phenotype

    • Cohorts

      Please, contact us

    • Observational trials

       

      PREMICLOSE Registry: Transcatheter closure of PDA in preterm babies, 70 patients 

      Sponsor M3C, Necker Enfants-Malades hospital

       

      MELODY Registry: Transcatheter pulmonary valve implantation, 45 patients

      Sponsor Medtronic

       

      Fetal aortic stenosis Registry: 15 patients

      Sponsor M3C

       

      FRANCISCO Registry: Observatoire Français des Communications Interventriculaires Congénitales avec hyperdébit pulmonaire

      Sponsor Société Française de Cardiologie

       

      CARREG (CARdiac congenital defects and REGulation genes) Registry: 4,398 patients

      Sponsor ARCFA

       

      BISMUTH Registry: Kawasaki disease, 93 patients

      Sponsor Inserm

       

      DCPT-FOIE Registry: Monitoring of liver functions in patients after Fontan operation, 26 patients

      Sponsor M3C

       

    • Patient samples

      Please, contact us

    Targets
    Therapeutics
    Clinical trials

    • NCT

       

      QUALI-REHAB study: cardiac rehabilitation program for teenagers and young adults with congenital heart disease, 4 patients

      Sponsor Novartis

Contacts

  • Nicolas Doulet

    Nicolas DOULET

    Business development manager

    • nicolas.doulet@institutimagine.org
    • +33 1 42 75 42 55

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